Popular Articles
Teeth Whitening Products

Targacept's TC-5214 Achieves All Primary And Secondary Outcome Measures In Phase 2b Trial As Augmentation Treatment For Major Depressive Disorder
Targacept, Inc. (NASDAQ: TRGT) today announced positive top-line results from a double blind, placebo controlled, flexible dose Phase 2b clinical trial of TC-5214 as an augmentation (add-on) treatment for major depressive disorder, or MDD, in subjects who did not respond adequately to first-line treatment with citalopram alone. The result on the primary outcome measure for the trial, mean change between treatment (TC-5214 + citalopram) and placebo (placebo + citalopram) from baseline on the Hamilton Rating Scale for Depression-17, or HAM-D, was highly statistically significant in favor of TC-5214 (p Next Steps
generic viagra online
High Levels Of Type Of Cholesterol Not Routinely Screened Linked To Heart Attacks
A genetic analysis from three studies of people living in Denmark found that those who had higher levels of a cholesterol known as lipoprotein
News of the day
Circumcising Men With HIV Did Not Protect Women, Trial Stopped Early
Early results of a trial in Uganda showed that circumcising men with HIV did not protect their female partners, and as circumcision does not
Medical Devices

A Rush Of Blood To The Head - Anger Increases Blood Flow

Mental stress causes carotid artery dilation and increases brain blood flow. A series of ultrasound experiments, described in BioMed Central"s open access journal Cardiovascular Ultrasound, also found that this dilatory reflex was absent in people with high blood pressure. Tasneem Naqvi and Hahn Hyuhn from the University of Southern California and Cedars-Sinai Medical Center evaluated carotid artery reactivity and brain blood flow in response to mental stress in 10 healthy young volunteers (aged between 19 and 27 years), 20 older healthy volunteers (aged 38 to 60 years) and in 28 patients with essential hypertension (aged 38 to 64 years). They found that in healthy subjects, mental stress caused vasodilation. This was accompanied by a net increase in brain blood flow. In hypertensive subjects, mental stress produced no vasodilation and no significant change in brain blood flow. During the experiments, the volunteers were set a series of tasks designed to provoke mental stress, including reading, arithmetic and anger recall tests. The researchers used ultrasound imaging to measure the effects of this activity on the carotid artery and an artery within the brain, while also measuring blood pressure and heart rate. According to Naqvi, "Inappropriate vasoconstriction, or lack of dilation in response to mental stress in stable coronary heart disease, contributes to the genesis of myocardial ischemia and confers an increased risk in patients with coronary artery disease. It will be interesting to see whether the lack of mental stress induced dilation we found defines subjects at increased risk of future cerebral events". Lack of required blood flow increase to the brain during mental activities may potentially affect cognition and cerebral performance during complex cerebral tasks. BioMed Central Limited


Add your comment:
Name:
Site address: http://
Your message:
Enter today\\\\'s date, 2 digits
(spam protection):