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Rates Of Severe Childhood Obesity Have Tripled
Rates of severe childhood obesity have tripled in the last 25 years, putting many children at risk for diabetes and heart disease, according to a report in Academic Pediatrics by an obesity expert at Brenner Children"s Hospital, part of Wake Forest University Baptist Medical Center.
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AARP Analysis Debunks Biologic Drug Industry Myth Association Presses Congress To Bring Less Costly Generics To Market Faster
A new analysis by AARP"s Public Policy
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Incyte Provides Update On Special Protocol Assessment For INCB18424 As A New Treatment For Myelofibrosis
Incyte Corporation (Nasdaq:INCY) announced that based on recent input from the U.S. Food and Drug Administration (FDA) regarding Incyte"s request for a Special Protocol Assessment (SPA) for INCB18424 for patients with primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (PPV-MF) and post-essential thrombocythemia myelofibrosis (PET-MF), it is clear that the most appropriate single primary endpoint for Incyte"s U.S. Phase III trial is the proportion of treated patients achieving a 35% reduction in spleen volume as compared to patients receiving placebo.
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Allergy Season: Cigarettes To The Rescue?

Everyone knows that smoking can kill you, but did you know that it may help with your allergies? A new study shows that cigarette smoke can prevent allergies by decreasing the reaction of immune cells to allergens. Smoking can cause lung cancer, pulmonary disease, and can even affect how the body fights infections. Along with many harmful effects, smoking cigarettes has a surprising benefit: cigarettes can protect smokers from certain types of allergies. Now, a study recommended by Neil Thomson, a member of Faculty of 1000 Biology and leading expert in the field of respiratory medicine, demonstrates that cigarette smoke decreases the allergic response by inhibiting the activity of mast cells, the major players in the immune system"s response to allergens. Researchers at Utrecht University in the Netherlands found that treatment of mast cells with a cigarette smoke-infused solution prevented the release of inflammation-inducing proteins in response to allergens, without affecting other mast cell immune functions. The mast cells used in the study were derived from mice, but it is likely that the same anti-allergy effect will hold true in humans. While taking up smoking to cure allergies is unwise, Thomson concludes that the findings presented in this study are "consistent with a dampening of allergic responses in smokers." Kathleen Wets Faculty of 1000: Biology and Medicine


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