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Cooling Therapy For Cardiac Arrest Survivors Is As Cost-Effective As Accepted Treatments For Other Conditions
Cooling unconscious cardiac arrest survivors can increase survival and has a cost effectiveness comparable to other widely accepted treatments in modern health care, researchers report in Circulation: Cardiovascular Quality and Outcomes.
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British Medical Journal Examines Recent Progress In Treating Neglected Diseases
The British Medical Journal examines the outcome of the Drugs for Neglected Diseases initiative meeting held in Nairobi, Kenya, last week. More than 200 international health experts came together to discuss finding therapies for such diseases as visceral leishmaniasis, Chagas disease and sleeping sickness. "Current treatments are often toxic, prohibitively expensive, or difficult to administer in countries with limited res," and "[d]rug companies have little incentive to develop treatments for neglected diseases that mainly affect poor people," the journal writes.
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Families Of Sudden Unexplained Death Victims Should Receive Comprehensive Cardiogenetic Testing
Relatives of a young person who dies suddenly should always be referred for cardiological and genetic examination in order to identify if they too are at risk of sudden death, a scientist told the annual conference of the European Society of Human Genetics. Dr. Christian van der Werf, a research fellow at the Department of Cardiogenetics, Academic Medical Centre, Amsterdam, The Netherlands said that, although his team"s research showed that inherited heart disease was present in over 30% of the families of sudden unexplained death (SUD) victims, the majority of such relatives were currently not being referred for examination.
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Biological Warfare In Bacteria Offers Hope For New Antibiotics

Scientists are to study a group of proteins that are highly effective at killing bacteria and which could hold the key to developing new types of antibiotics. Researchers from the Universities of York and Leeds have been awarded ÷£3.3m from the Biotechnology and Biological Sciences Research Council (BBSRC) to find out how a family of proteins known as colicins force their way into bacterial cells before destroying them. The team, led by Professor Colin Kleanthous, from the University of York"s Department of Biology, will develop earlier research that suggests colicins use decoys to mimic key parts of the cells" own protein machinery to evade their defences. Professor Kleanthous said: "Colicins are the weapon used in the biological warfare that takes place between competing bacteria. Understanding how this group of proteins work could help scientists develop new drug delivery methods to target the bacteria that cause diseases in people." "It"s as though the colicins are carrying the equivalent of hand grenades which they can deploy without harming themselves," said Professor Sheena Radford of the University of Leeds" Faculty of Biological Sciences. The five year programme of research aims to discover how colicins specifically penetrate Gram-negative bacteria which are protected by two membrane barriers. It will involve collaboration between six groups of scientists from the Departments of Biology and Chemistry at the University of York and the Astbury Centre for Structural and Molecular Biology, Faculty of Biological Sciences, at the University of Leeds. York University


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