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Insights Into Failed HIV-1 Vaccine Trial: Study
Following the disbandment of the STEP trial to test the efficacy of the Merck HIV-1 vaccine candidate in 2007, the leading explanation for why the vaccine was ineffective - and may have even increased susceptibility to acquiring the virus - centered on the hypothesis that high levels of baseline Ad5-specific neutralizing antibodies may have increased HIV-1 acquisition among the study subjects who received the vaccine by increasing Ad5-specific CD4+ T-cells that were susceptible to HIV-1 infection.
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Frontal Cerebral Hypothermia Found To Be Possible New Treatment For Insomnia
Insomnia is associated with increased frontal cerebral metabolism during Rapid Eye Movement (REM) sleep. Cerebral hypothermia, or cooling of the brain, has been found to reduce cerebral metabolism in other medical conditions, but its effects in insomnia are unknown.
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Doctors And Nurses Facing Tough Choices
Doctors and nurses consider job security and the differences between primary care and specialties when choosing their career paths.
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RCP President Reponds To New ONS Figures Suggesting That School Pupils Are More Likely To Drink Alcohol If They Live With Other Drinkers, UK

Responding to data in Smoking, drinking and drug use among young people in England, 2008 that suggests the likelihood of a pupil drinking alcohol increases with the number of drinkers per household, Professor Ian Gilmore, President of the Royal College of Physicians said: "These figures show very clearly that we need to tackle teenage drinking from every possible angle. While it"s absolutely right to focus on issues of price, and illegal sales it is equally vital that parents, teachers and other role models acknowledge that their own behaviour shapes children"s attitudes towards alcohol. In a sense this cuts to the heart of what we mean when we talk about our drinking culture. If we are to encourage healthier attitudes among the young, adults need to think more carefully about the examples we set for our children." Notes 1. As well as being President of the Royal College of Physicians, Professor Ian Gilmore is also Chair of the Alcohol Health Alliance UK. Royal College of Physicians


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