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Antiabortion-Rights Groups To Reintroduce Colorado Personhood Initiative
Colorado Right to Life and Personhood USA are proposing a 2010 state ballot initiative with a different version of 2008"s defeated "personhood" amendment to the state constitution, the Colorado Springs Gazette reports. The groups intend to submit their proposal to the Colorado Legislative Council this week. In the November 2008 election, 73% of state voters opposed the previous version, known as Amendment 48, which was sponsored by Colorado for Equal Rights.The new version includes modified language that its supporters say will clarify its intent. Rather than defining a person as "any human being from the moment of fertilization," the new version would establish personhood as "every human being from the beginning of the biological development of that human being." The initiative"s sponsors also said that they will be better funded and articulate a clearer message than in 2008, when a college student launched the campaign.According to the Gazette, abortion-rights supporters "weren"t overly concerned" about the new initiative. Jacy Montoya, head of the Colorado Organization for Latina Opportunity and Reproductive Rights, said that the 2008 vote demonstrated that Colorado residents are "uncomfortable with the government and strangers making personal decision for families." Lynn Paltrow, executive director of National Advocates for Pregnant Women, said that the new attempt "gives us another opportunity to explain how personhood amendments threaten all pregnant women, including those going to term" (Barna,Colorado Springs Gazette, 6/29).
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Controversial Cancer Stem Cells Offer New Direction For Treatment
In a review in Science, a University of Rochester Medical Center researcher sorts out the controversy and promise around a dangerous subtype of cancer cells, known as cancer stem cells, which seem capable of resisting many modern treatments.
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Amicus Therapeutics Commences Phase 3 Trial Evaluating Amigal(TM) For The Treatment Of Fabry Disease
Amicus Therapeutics (Nasdaq: FOLD) announced it has commenced the U.S. registration Phase 3 trial with its investigational drug, Amigal(TM) (migalastat hydrochloride) for the treatment of Fabry disease. The Company has reached agreement with the U.S. Food and Drug Administration (FDA) on the key protocol design elements of the pivotal trial, including the use of the surrogate primary endpoint of the change in the amount of kidney interstitial capillary GL-3, the substrate that accumulates in the cells of Fabry patients. In addition, the FDA is in agreement that the Company is eligible to seek Accelerated Approval for Amigal according to Subpart H regulations. The Company has begun submitting the Phase 3 protocol to investigational sites worldwide and expects to begin the dosing of subjects in the second half of this year.
Public Health

Testing For Norovirus And Enterovirus Is Becoming Increasingly Important And Commonplace

High profile outbreaks associated with the viruses have kept EMSL Analytical scientists busy. Pollution of rivers and recreational waters by sewage and animal fecal waste has led to a number of high profile human gastrointestinal infections in recent years. Many of these same contaminants can be passed from human to human by direct contact with secretions from an infected person or by contacting contaminated surfaces. Monitoring environmental microorganisms such as bacteria and viruses is an important method for the prevention of human diseases. Frequent outbreaks of the two viruses, enterovirus and norovirus; have caused particularly serious environmental health concerns in numerous high profile cases. According to the CDC, "Noroviruses are highly contagious and as few as 10 viral particles may be sufficient to infect an individual." Enteroviruses are believed to cause between 30 and 50 million infections in the United States alone each year. EMSL Analytical, a leading environmental testing laboratory, has been busy utilizing advanced PCR technologies to test environmental samples for the viruses. Advances in testing methods have produced several PCR-based methods that now do not require animal cultures for analysis, improving the analytical process. "In the PCR-based rapid detection methods, virus particles in water samples are captured on aluminum chloride coated negative charged HA membranes," reported Charlie Li, Ph.D., PCR Laboratory Director at EMSL Analytical. "The viruses are then eluted out and concentrated using ultra-filtration. Viral RNA is then isolated from the eluted virus. Using a one-step reverse transcription real-time PCR, virus RNA are converted to DNA, then detected with a sensitive and specific real-time PCR." Clearly, the tests provide an approach for rapid monitoring of the viruses and other additional human viral pathogens. To learn more about norovirus or enterovirus contact EMSL Analytical at 800-220-3675 or visit http://www.EMSL.com. EMSL Analytical, Inc.


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