Endocrinology
Hives are also known as urticaria, welts, wheals, or nettle rash. It is a red, raised, itchy skin rash that is sometimes triggered by something that produces an allergic reaction - an allergen. When there is an allergic reaction the body releases a protein called histamine. When histamine is released our capillaries (tiny blood vessels) leak fluid. The fluid accumulates in the skin and causes a rash.
U.S. Department of Health and Human Services (HHS) Secretary Kathleen Sebelius announced today that the United States Senate unanimously confirmed Dr. Nicole Lurie as the next Assistant Secretary for Preparedness and Response at HHS. Dr. Lurie, an internationally recognized leader in public health, most recently served as co-director of the RAND Corporation Center for Domestic and International Health Security, senior natural scientist and professor of policy analysis at the RAND Corporation.
If you believe everything you read, "health and safety" is to blame for a lot of fun events being cancelled. Plastic duck races, ice cream toppings and even Morris Dancing have all allegedly fallen victim to excessive health and safety regulations.
Fate of 27,000 ER Patients Per Year Hangs in Balance as Supervisors Consider Withdrawing County"s Authority to Convert Acute-Care Hospital into a Rehab Center
A pet bites a child, and the owner is faced with an excruciating decision: Is it safe to keep this dog?
The death toll from three of the UK"s most common cancers has dropped to its lowest level for almost 40 years* - according to new figures released by Cancer Research UK.
A new national service which will provide comprehensive care and support
Doctors at the University of Kentucky Chandler Medical Center-Markey Cancer Center compared symptom analysis to ultrasound in predicting ovarian cancer. They selected 272 women participating in annual trans-vaginal screening (TVS) from 31,748 women enrolled in a free screening project at the university, comparing symptom results to ultrasound and surgical pathology findings.
More and more children are participating and getting hurt playing sports each year. A
safefood today launched a new advertising campaign to highlight common and widespread poor food hygiene practices in the home as new research (1) revealed that 84% of people did not thoroughly wash their hands after handling raw chicken. The campaign titled "Don"t Take Risks" focuses on key messages of proper hand washing, proper cleaning of cooking utensils and thorough cooking, steps all of which can help minimise the risks of food poisoning in the home. The research also revealed that 72% failed to properly wash a knife used in preparing raw chicken before its reuse on salad vegetables, and 56% did not check if the chicken was cooked properly.
The Department of Health and Human Services (DHHS) will hold six public hearings July 16, 2009. These hearings will take place in Lincoln at the State Office Building, 301 Centennial Mall South, lower level conference room A. The hearings are being held to accept comments on proposed regulations.
One in seven young adults in Canada is deficient in vitamin C, according to a first-of-its kind study published today. The findings, published in the American Journal of Epidemiology, suggest that young adults with a vitamin C (ascorbic acid) deficiency have significantly higher waist circumference, body mass index, inflammation and blood pressure - indicators of chronic disease and obesity - than do people with adequate blood levels of vitamin C.
More than 5,600 Louisiana tobacco users received free medication last month to help overcome their addiction to tobacco. The initiative was part of a statewide promotion to assist with tobacco cessation by providing a month"s supply of nicotine replacement therapy patches to residents trying to quit tobacco products.
The Harley Medical Group has revealed that the number of nipple correction surgical procedures carried out has risen 30% year-on-year. Mr Riccardo Frati, surgeon at The Harley Medical Group, appeared on GMTV to discuss nipple correction surgery with Lorraine Kelly. He said: "There are nipple surgery options out there and a minority of women seek to change the size or shape of their nipples through reconstructive surgery purely for cosmetic reasons. Another option, nipple elevation, involves the nipple being raised above its existing level to enhance its appearance and make the breast look more pert.
Results from a study published by the University of Michigan have shown that as many as 15% of women in the study group determined to be negative for the presence of human papillomavirus (HPV) in the cervix, via the most commonly used test for HPV DNA, may actually be infected with the virus at clinically relevant viral loads. PCR-MS detected the presence of high-risk HPV in nearly half (46.7%) of women who tested negative by the Hybrid Capture 2 (HC2) test, which is standard of care in many countries. Approximately 9,000 American women are diagnosed with cervical cancer each year despite regular cervical screening. The study, titled, Development and Evaluation of a PCR and Mass Spectroscopy-based (PCR-MS) Method for Quantitative, Type-specific Detection of Human Papillomavirus, will be published in the September 2009 edition of Journal of Virological Methods. The assay used in this study is exclusively licensed by SEQUENOM (Nasdaq: SQNM).
El Salvador and Benin have marked World Asthma Day by placing orders with the Asthma Drug Facility (ADF). Through the ADF these and other low- and middle-income countries will be able to obtain quality-assured essential asthma medicines at affordable prices for the first time.
Cepheid (Nasdaq: CPHD) announced it has received clearance from the U.S. Food & Drug Administration (FDA) to market its Xpert(R) C. difficile test, an on-demand molecular diagnostic test designed for 45-minute detection of the bacterium that causes Clostridium difficile infection (CDI). The Xpert C. difficile test is the first test for CDI to deliver both rapid turnaround and a high degree of accuracy.
Memories aren"t made of actin filaments. But their assembly is crucial for long-term potentiation (LTP), an increase in synapse sensitivity that researchers think helps to lay down memories. In the July 13, 2009 issue of the Journal of Cell Biology, Rex et al. reveal that LTP"s actin reorganization occurs in two stages that are controlled by different pathways, a discovery that helps explain why it is easy to encode new memories but hard to hold onto them.
The School Nutrition Association"s 2008 National School Lunch Week Campaign, "Vote for School Lunch - Presidential Edition," was honored by the American Society of Association Executives (ASAE) with a 2009 Summit Award. The award will be presented to SNA during the 10th Annual Summit Awards Dinner, September 29, 2009 at the National Building Museum in Washington, DC.
On Friday, the House Appropriations Labor, HHS, Education and Related Agencies Subcommittee approved by voice vote a $730.5 billion spending bill to fund the Departments of Labor, Health and Human Services, and Education, CQ Today reports. The bill shifts funding away from abstinence-only sex education toward more comprehensive pregnancy prevention programs. The bill would allocate $114.5 million for a "teenage pregnancy prevention initiative" that offers "evidence-based and other approaches, such as abstinence." The measure continues several prohibitions on using federal funds to cover abortion and restrictions on funding for embryo research (Wolfe, CQ Today, 7/10).The measure includes $73.7 billion in discretionary spending for HHS, $2 billion more than President Obama requested (Hunt, CongressDaily, 7/10). The full committee is scheduled to mark up the bill on July 17 (CQ Today, 7/10).
"I stood up and applauded for women everywhere when I heard the news" that the United Nations Human Rights Council, including the U.S., "recognized maternal death as a human rights issue," CARE President and CEO Helene Gayle writes in an Atlanta Journal-Constitution opinion piece. Gayle writes that governments for the past 15 years "have failed to meet the commitments made and targets set to reduce the more than half a million maternal deaths every year."According to Gayle, preventing maternal death "requires three well-coordinated actions: sustain political leadership, secure adequate res and strengthen health systems." She adds that the resolution "is a positive step" but that it is "only effective if it translates into action." She continues, "It"s great to see the Obama administration places women and girls high on the agenda," adding that many members of Congress also support these issues.Reducing maternal mortality "requires significant res," Gayle writes. She adds, "To be blunt, an estimated global commitment of $39 billion over 10 years is needed to make significant progress." Such a commitment would be "an investment in women, their families and the economic productivity of nations," according to Gayle."The cost of not investing is far greater," Gayle continues. She notes that women "do two-thirds of the world"s work and produce nearly 60% of the world"s food." In addition, "children who lose their mothers are 10 times more likely to die in childhood than children with mothers," and maternal and newborn deaths "represent an estimated annual loss of $15.5 billion in productivity," according to Gayle. "Clearly, other development goals cannot be met without healthy mothers," she adds.She continues that the "most tragic and infuriating point" is that the "death of a woman in childbirth is one of the most inexcusable deaths on earth." Because high maternal mortality is a "barometer of weak health systems, often reflecting the low status of women," strengthening health systems to improve maternal health will therefore enable the system to "address other health needs," Gayle writes. She adds that countries such as Bangladesh, Ethiopia and Peru have improved mortality rates "through four lifesaving programs: family planning, skilled and culturally sensitive care during pregnancy and childbirth, emergency care for complications and postpartum care."Gayle writes, "The U.S. can spearhead a comprehensive maternal health action plan and, by doing so, set an example for world leaders to join and invest in." She concludes, "The actions we take now can make maternal death a problem of the past and not one of our children"s future" (Gayle, Atlanta Journal-Constitution, 7/10).
Although New York state"s decision to allow state-funded embryonic stem cell researchers to compensate women for donating their eggs "has provoked criticism from some ethicists and runs counter to guidelines issued by" NIH and the National Academy of Sciences, it still "seems justifiable" to pay the women "for undergoing an arduous procedure and to spur progress on potentially important research that has been slowed because of a lack of human eggs," a New York Times editorial states. The state"s Empire State Stem Cell Board last month made the decision to allow researchers to pay women up to $10,000 as compensation.According to the editorial, "[w]omen already get paid comparable sums to donate their eggs to help infertile women have a child through in vitro fertilization," so it "is hard to see why they should not be paid for contributing their eggs for research." The editorial notes that the "money is meant as reimbursement for travel, housing, child care or medical expenses," and it also would "compensate the women for the considerable time, burden and inconvenience of harvesting their eggs, a process that can take 56 hours spread out over many weeks.""The board set reasonable constraints, insisting that the research be rigorously reviewed and approved by oversight committees, that donors be fully informed of potential physical and psychological risks and that they give informed consent to the procedure," the editorial states. It adds, "One concern has been that payments could induce women, especially poor women, to provide eggs without fully considering potential risks." The editorial continues, "In an effort to mitigate that possibility, the stem cell board will follow the guidelines of the American Society of Reproductive Medicine, which require justification for payments of $5,000 or more and deem sums above $10,000 inappropriate."The editorial adds, "Human eggs are highly prized for some of the most promising research, notably studies that require matching embryonic stem cells to a particular patient with a particular disease," concluding, "It has proved almost impossible to recruit women to go through the arduous process for free," so the "board was right to allow fair compensation" (New York Times, 7/11).
Rural Americans are hopeful that health reform includes funding for clinics and health care services in their communities, where the cost of care is often high, CNN reports.
"For entrepreneurs trying to start or run a business, the obstacles are huge. But few loom as large as one: health care," the Wall Street Journal reports. "At some businesses, in fact, health care is the highest expense after salaries - with devastating consequences. Owners must skimp on vital investments like marketing and research. Some can"t hire the people they want because top candidates demand premium coverage. Or they end up understaffed because of the high cost of insurance - and lose potential clients as a result. At the same time, to keep costs in check, countless companies are slashing coverage or dropping it entirely. Some are turning to freelancers or offshore workers instead of hiring full-timers and locals. And some would-be entrepreneurs find insurance so onerous that they"re not even starting a business in the first place."
The American Society of Hematology (ASH) announces the five 2009 recipients of the ASH Research Training Award for Fellows, a grant that encourages junior researchers to pursue careers in academic hematology by supporting protected time to conduct research during their fellowship training.
Alejandro Gutierrez, MD, is the third recipient of the ASH-AMFDP grant, an award designed to help increase the number of underrepresented minority scholars in the field of hematology, and will begin his research into the pathogenesis of T-cell acute lymphoblastic leukemia (T-ALL) this month. The award, the result of a partnership between the American Society of Hematology (ASH) and the Harold Amos Medical Faculty Development Program (AMFDP) of the Robert Wood Johnson Foundation, provides four years of support, including an annual stipend of up to $75,000 and an annual grant of more than $29,000 for research activities.
The Pennsylvania House last week voted to approve a bill that allows state residents up to age 29 to be added to or remain on their parents" health insurance plans as long as they live in the state or are full-time students, the Harrisburg Patriot-News reports. They also must be single and not have dependents.According to national data, young adults between ages 19 and 29 make up the largest segment of the U.S. population without health insurance. The Pennsylvania Insurance Department estimates that nearly 400,000 state residents in that age group are uninsured. The bill allows employers to decide if they want to offer the coverage option to their employees. Families choosing to add adult dependents to their health plans will have higher premiums. Gov. Ed Rendell (D) is expected to sign the bill, which the state Senate approved in March (Thompson, Harrisburg Patriot-News, 5/14). Prescription for Pennsylvania Plan
HHS Secretary Kathleen Sebelius said Sunday the U.S. has agreed to put an addition $1 billion towards ingredients for the production of a vaccine that offers protection against the H1N1 (swine flu) virus, Reuters reports. "There"ll be another $1 billion worth of orders placed to get the bulk ingredients for an H1N1 vaccination. Congress has agreed with the president that this is the number one priority, keeping Americans safe and secure," Sebelius said (7/12).
A new national study finds kids are being hurt in bathtubs and showers at a surprising rate.* You might think scalding or near drownings would be the most common threat in the bathroom, but they"re not.
Condom use is associated with a reduced risk of contracting herpes simplex virus 2, according to a report based on pooled analysis of data from previous studies in the July 13 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
The beta-carotene in so-called "Golden Rice" converts to vitamin A in humans, according to researchers at Baylor College of Medicine and Tufts University in an article that appears in the current issue of the American Journal of Clinical Nutrition.
The NPHS influenza surveillance scheme, which records reports of diagnoses of flufrom more than 300 GP practices across Wales, shows low levels of influenza activity in all parts of Wales. Further detail can be found on the NPHS website: http://www.wales.nhs.uk/sites3/page.cfm?orgid=457&pid=38241
The tiny translucent egg nestled in the special laboratory gel was a mere 30 days old, but its four-week birthday caused researchers to quietly celebrate. This was the first time anyone had successfully grown a woman"s immature egg cells, contained in a tiny sac called a follicle, to a healthy and nearly mature egg in the laboratory. When an egg is fully mature, it is ready to be fertilized.
The number of people with Alzheimer"s and dementia - both new cases and
Many of the approximately one million Canadians(i) living with psoriasis may be faced with physical or emotional challenges as they struggle with public misperceptions and stigmas of this painful, chronic immune disorder that affects the skin. Now, a Leger Marketing survey of Canadians with psoriasis, pSoriasis Knowledge IN Canada (SKIN), reveals that the debilitating skin condition presents a substantial problem for them in their daily lives. The SKIN survey, which included questions about burden of illness, revealed that two-thirds (66 per cent) of SKIN respondents agreed with the statement that psoriasis ranks among the top two illnesses in terms of its impact on quality of life (QoL) out of ten of the worst diseases, including cancer, heart disease, diabetes and arthritis.(1) Of those SKIN respondents who stated that their psoriasis "sometimes" or "very often" caused them problems in their personal or social relationships, and difficulties with normal daily activities when it was not in control, almost 60 per cent indicated that their disease was
Southampton University Hospitals NHS Trust is to host a national conference on combating infections.
The following statistics were released today by the Department of Health:
RNs from the California Nurses Association/National Nurses Organizing Committee (CNA/NNOC) have filed an urgent plea with the state of California to step in and force Sutter Solano Hospital to provide nurses with proper safety equipment when they care for patients infected with the H1N1 "swine flu" virus. The nurses fear that the unsafe procedures at the hospital create a danger of infection for every patient at the facility, as well as for the surrounding community.
"President Obama signaled recently a major shift in the way the United States tries to help poor countries," Philip Stevens, policy director at the International Policy Network, writes in a Providence Journal opinion piece, adding, "Whereas the Bush presidency pushed to spend enormous sums on individual high-profile diseases such as AIDS, Obama says he will broaden U.S. aid to improve health more generally." However, Stevens writes that the "$63 billion question remains (for that is the sum proposed by Obama): Is it likely to help improve health over the long term?" He adds, "Because far more people in poor countries die of preventable diseases like pneumonia than AIDS, the plan makes some sense. But, heartless as it seems, health care programs funded by foreign aid rarely if ever live up to the soaring rhetoric with which they are launched by politicians." According to Stevens, "[s]tudy after study shows that health aid makes almost no difference to mortality rates and health outcomes, despite the expenditure of billions." He adds, "In happier economic times, indefinitely financing state health care in Africa may have imparted a warm humanitarian glow to U.S. taxpayers. Now that times are harder, and it is clear such transfers rarely work, maybe it"s time to pare them right back." Stevens writes, "When governments become dependent on foreign s to maintain their activities, it drives a wedge between them and their citizens and allows corrupt and repressive governments to remain in power." It also "discourages governments from enacting the politically difficult reforms needed to promote economic development strengthening the rule of law, establishing property rights and opening markets," Stevens writes, adding, "Without improving prosperity, you can"t improve health care."He concludes, "Fortunately, the recession has accelerated recent declines in foreign aid. Congress still has to approve the funds so it has a chance to end subsidies to corrupt governments and being a new chapter for the world"s poorest people" (Stevens, Providence Journal, 5/17).
A new review of existing research says there is little evidence to support mandatory hearing-loss prevention programs at the workplace.
Research released at the International Conference on Alzheimer"s Disease suggests that adhering to a Mediterranean diet may decrease risk of dementia.
Blacks and others with darker skin might be at greater risk for tobacco addiction than whites and those with lighter skin because the greater the amount of melanin, the coloring pigment in skin, the more nicotine appears to be stored, according to preliminary findings published in the journal Pharmacology, Biochemistry and Behavior, the New York Times reports. For the study, lead researcher Gary King, a professor of biobehavioral health at Pennsylvania State University, looked at 150 black smokers and measured their levels of melanin and cotinine, a byproduct of nicotine. They also surveyed the participants to determine the level of their smoking habit. Those with the most melanin were found to smoke the most and have the most cotinine in their system. They also had the highest level of dependence on tobacco. The findings might indicate why some people are more affected by nicotine than others, according to the study (Nagourney, New York Times, 5/19).
A USA Today/Gallup Poll found that "most Americans say it"s important to overhaul health care this year," but "they are less enthusiastic about some of the proposals to pay for it," USA Today reports. "And while a majority say controlling costs should be the legislation"s top goal, more than nine in 10 oppose limits on getting whatever tests or treatments they and their doctors think are necessary." But some good news for President Obama: "A third of those surveyed say they trust him and congressional Democrats most when it comes to changing health care, compared with 10% who choose congressional Republicans. Another 45% trust doctors and hospitals the most."
A new federal rating system to track quality gives nursing homes mixed reviews. The Centers for Medicare and Medicaid Services (CMS) developed the Nursing Home Compare Web site, which compares the nation"s 15,600 homes. There were complaints that the old site was unmanageable.
Obesity, among other factors, is strongly associated with an increased risk of rapid cartilage loss, according to a study published in the August issue of Radiology.
"Secretary of State Hillary Clinton said Monday she is frustrated over the failure" to name a new head of the USAID, despite it being a priority for the administration, AFP/Google.com reports. "Clinton, addressing USAID staff who asked why there was no administrator and deputy six months into President Barack Obama"s administration, complained about what she called an increasingly burdensome vetting process," the news service writes (7/13).
"Swiss drug company Novartis AG and the Institute for OneWorld Health, a nonprofit group, will announce this week a partnership to discover drugs for a type of diarrhea that kills about 1.6 million children each year in the developing world," the Wall Street Journal reports.
To mark World Population Day on July 11, U.N. officials are calling for investment in women and girls during the global financial crisis as a way to promote economic recovery and tackle poverty and inequality, afrol News reports. "There is no smarter investment in troubled times," Thoraya Ahmed Obaid, executive director of UNFPA, said. According to Obaid, even before the financial downturn, women and girls were the majority of the world"s poor. "Now, they are falling deeper into poverty and face increased health risks, especially if they are pregnant," she said, adding that the "health gap" will get bigger "unless we increase social investments, maintain health gains and expand efforts to save more women"s lives."
NICE today welcomed the Office for Life Sciences new Blueprint to support the life sciences industry, which will also improve patient access to innovative new drugs.
Four members of the Medical Research Council community were recognised for their contribution to science by the Royal Society.
The human brain can adapt to changing demands even in adulthood, but MIT neuroscientists have now found evidence of it changing with unsuspected speed. Their findings suggest that the brain has a network of silent connections that underlie its plasticity.
The interaction between a network of altered genes appears to play an important role in the development and progression of brain tumors, according to a study in the July 15 issue of JAMA.
The biopharmaceutical company PAION AG (ISIN DE000A0B65S3; Frankfurt Stock Exchange, Prime Standard: PA8) today announces that the respective Data Monitoring Committees (DMCs), after predefined interim analyses, recommended that the Company should proceed as planned with their Phase IIa study as well as Phase Ib of CNS 7065, a new short-acting intravenous anesthetic/sedative.
Luminex Corporation (NASDAQ: LMNX), the worldwide leader in multiplexed solutions, today announced that the U.S. Food and Drug Administration (FDA) has cleared labeling updates for the company"s xTAG® Respiratory Viral Panel (RVP) to include data about the performance of the test in humans infected with the pandemic strain of influenza A, 2009 influenza A/H1N1, which is sometimes referred to as "swine flu." The test"s labeling has been updated to include information from two new studies that demonstrate that xTAG RVP can be an effective aid in the detection of 2009 Influenza A/HIN1, but cannot identify the hemagglutinin gene of the 2009 Influenza A/H1N1 in clinical specimens.
GenWay Biotech, Inc., a US-based diagnostic company has become CLIA certified and received a California lab license. Their license currently permits the testing of immunological biomarkers. This is a very important step in the direction of commercialization of the novel innovative diagnostic tests currently being developed at GenWay. In upcoming weeks, GenWay will add new cancer biomarker tests to their portfolio as well as several infectious diseases such as sexual transmitted diseases. GenWay is seeking to obtain CAP accreditation by the end of the year.
Researchers at the University of Rochester have developed a mathematical model to predict immune responses to infection with influenza A viruses, including novel viruses such as the emergent 2009 influenza A (H1N1). This model examines the contributions of specific sets of immune cells in fighting influenza A virus. The model also helps predict when during the immune response to viral infection antiviral therapy would be most effective.
New insights into how a Phase III Alzheimer"s drug might work were among the advances in potential therapies targeting two abnormal brain proteins - beta amyloid and phosphorylated tau - at ICAD.
Health reform may succeed in creating better coverage and access for Americans, but until we reduce the barriers to proper medication adherence, many patients will not experience improved health, according to experts meeting today to discuss the challenges of adherence.
Scientists have sequenced the genome of the parasite that causes intestinal schistosomiasis (also known as bilharzia or snail fever), a devastating tropical disease that afflicts more than 200 million people in the developing world.
Medtronic, Inc. (NYSE: MDT) announced completion of a 12-month follow up in the STOP-AF (Sustained Treatment of Paroxysmal Atrial Fibrillation) clinical trial evaluating the first cryoballoon catheter technology designed to treat paroxysmal atrial fibrillation - the Medtronic Arctic Front® CryoAblation Catheter System. Atrial fibrillation (AF) is the most common arrhythmia affecting more than 3 million Americans and 7 million people worldwide.1 After the study data are analyzed and filed with regulatory authorities, the results will be shared at an upcoming medical meeting. The system is approved for use in Europe, Australia and Hong Kong and is under investigational use in the United States.
Basilea Pharmaceutica Ltd. (SWISS: BSLN) announces that the National Institute for Health and Clinical Excellence (NICE) issued the Final Appraisal Determination (FAD) recommending the use of Toctino® (alitretinoin) within its licensed indication, as a treatment option for adults with severe chronic hand eczema that has not responded to potent topical corticosteroids.
CQC publishes national review of NHS child safeguarding
Kaiser Veterans Affairs hospitals and outpatient clinics under review are not always complying fully with federal privacy requirements, often exposing women when they bathe or receive exams, according to government auditors, The Associated Press reports.
Individuals with heart disease are twice as likely to suffer from depression as the general population, an association the medical community has largely been unable to explain. Now, a new study by researchers at The Miriam Hospital, in conjunction with The Montrç©al Heart Institute, University of Montrç©al and McGill University, reveals there may be genetic variations that contribute to depression in heart disease patients.
"Rising unemployment and spiking Medicaid and welfare caseloads have put [New Hampshire"s] most recent budget to the test just two weeks after its adoption," New Hampshire Public Radio reports. The state"s Medicaid caseload is just 39 enrollees away from putting the "state"s Medicaid budget in the red."
NPR reports on President Obama"s "broad global health strategy," which would increase the amount of funding for family planning, maternal and child health programs to about a "half billion dollars" next year. According to NPR, "the U.S. has committed $230 million [over the next five years] directly to health in Afghanistan, whose government has already built 2,000 health facilities since the collapse of the Taliban regime" (Wilson, 7/15).
Obama"s Policy Could Make U.S.-Africa Relations "Flower"
With the current outbreak of swine flu, and in the absence of a vaccine or treatment at present, the only way to contain the virus is to get people around the world to take precautionary measures. In a special editorial1 in the latest issue of Springer"s International Journal of Behavioral Medicine, Johannes Brug, Arja Aro, and Jan Hendrik Richardus show that there are three key parameters that convince people to take precautions. Firstly, they need to be aware of the risk to them. Secondly, they need to believe that effective protective actions are available and have confidence in them. Lastly, communications about risk need to be carefully managed so that they express the actual risk accurately to prevent mass scares.
A team of researchers has mapped patterns of illicit drug use across the state of Oregon using a method of sampling municipal wastewater before it is treated.
New England Cord Blood Bank, Inc. (NECBB), a global cord blood processing and storage facility, announced today that it will be implementing an automated blood processing system at the company"s Newton facility. The AutoXpress™ System (AXP), developed by ThermoGenesis Corp. and distributed by GE Healthcare, is a state-of-the-art, fully closed and sterile system that will provide automated cell separation and processing for cord blood samples, ensuring quality and consistency in cord blood processing while maximizing the yield of valuable stem cells from the cord blood.
PolyMedix, Inc. (OTCBB: PYMX), an emerging biotechnology company developing acute care products for infectious diseases and acute cardiovascular disorders, announced that the United States Patent and Trademark Office issued a patent assigned to PolyMedix relating to angiogenesis inhibitors. The patent, number 7,553,876, entitled "Polycationic Compounds and Uses Thereof," relates to therapeutic uses of PolyMedix compounds for inhibiting angiogenesis.
Just like a conductor cueing musicians in an orchestra, Fgf10, a member of the fibroblast growth factor (Ffg) family of morphogens, lets brain stem cells know that the moment to get to work has arrived, ensuring that they hit their first developmental milestone on time, report scientists at the Salk Institute for Biological Studies in the July 16, 2009, edition of the journal Neuron.
Diabetes patients taking NovoLog® (insulin aspart [rDNA origin] injection) can now use the insulin in their pump for up to six days following the U.S. Food and Drug Administration (FDA) approval of a labeling change, diabetes care company Novo Nordisk announced today.[i] The previous label allowed for NovoLog® to be stored in the pump reservoir for two days. This makes NovoLog® the first and only rapid-acting insulin with this extended in-use time.
Spectranetics Corporation (Nasdaq: SPNC) reported the first human procedures using its Turbo-Tandem™ System, which had earlier received FDA clearance and CE mark approval for marketing in the US and the EU. The Turbo-Tandem System is a single-use, disposable device indicated for atherectomy of infrainguinal arteries. It is comprised of two integrated catheters, a 7 French laser guide catheter in combination with a 2.0mm excimer laser ablation catheter, and is designed to perform atherectomy and ablation of plaque in arterial lesions above the knee, primarily within the superficial femoral and popliteal arteries.
Targacept, Inc. (NASDAQ: TRGT) today announced positive top-line results from a double blind, placebo controlled, flexible dose Phase 2b clinical trial of TC-5214 as an augmentation (add-on) treatment for major depressive disorder, or MDD, in subjects who did not respond adequately to first-line treatment with citalopram alone. The result on the primary outcome measure for the trial, mean change between treatment (TC-5214 + citalopram) and placebo (placebo + citalopram) from baseline on the Hamilton Rating Scale for Depression-17, or HAM-D, was highly statistically significant in favor of TC-5214 (p Next Steps
Today, more than 100 future physicians from across the nation will descend on Capitol Hill to lobby on upcoming health care reform legislation.
A review published Online First and in a future edition of The Lancet reports that men who have sex with men (MSM) in sub-Saharan Africa are a high risk group for HIV infection. However, religious, political, and social shame signify that this isolated group cannot access vital services. It is crucial that the HIV/AIDS community take action to deal with this crisis. The review discusses those issues and is the work of Dr Adrian D Smith, of the University of Oxford, UK, and his team.
Boston Scientific Corporation (NYSE: BSX) announced it has received approval from the U.S. Food and Drug Administration (FDA) to market its TAXUS((R)) Liberte((R)) Long Paclitaxel-Eluting Coronary Stent System, a next-generation drug-eluting stent (DES) designed for long lesions. At 38 mm, it is the longest available DES, providing doctors an option that can potentially reduce the number of stents used in more complex cases, simplifying procedures and reducing costs. It affords a more efficient treatment option for the estimated 8 to 10 percent(1) of patients with long lesions. The Company plans to launch the product in the U.S. next month. It received CE Mark approval in 2007.
PLC Systems Inc. (OTC Bulletin Board: PLCSF), a company focused on innovative cardiac and vascular medical device-based technologies, announced that a follow-up study of the landmark Cardiac Angiography in Renally Impaired Patients (CARE) Study determined that Contrast-Induced Nephropathy (CIN) is associated with long-term adverse events, ranging from pulmonary edema to death, and that patients with CIN were twice as likely as those who did not develop CIN to experience adverse events.
In a week that has seen the British swine flu death toll reach 29 and it is estimated that 55,000 people have caught the virus, hospitalizing 652 of them, the
Mental Health America today commended Senate and House health reform legislation for including mental health and substance use coverage in a benefit package.
All Department of Veterans Affairs outpatient clinics and hospitals are failing to fully comply with federal privacy standards for women, according to a Government Accountability Office report, the AP/Boston Globe reports. The report comes as thousands of female veterans are entering the VA health system after returning from Iraq and Afghanistan.GAO auditors said that many VA facilities had gynecological tables that faced the door. In one instance, a gynecological table faced a door opening to a waiting room. The investigation also found cases where women had to walk through waiting rooms to use the restroom -- a violation of VA policy requiring adjoining restrooms. Four VA hospitals did not guarantee women access to private bathing facilities. In two of those cases, the facilities did not have locks.Nearly 20% of female veterans have been diagnosed with post-traumatic stress disorder, and many of them have experienced sexual trauma while serving, according to the report. The report also said that most female veterans at VA facilities are ages 20 to 29. On average, female veterans using VA facilities are much younger than male VA patients, it noted.Randall Williamson, director of health care issues at GAO, said that although top VA officials are committed to improving care for female veterans, facilities are not always taking simple steps, such as repositioning exam tables. Patricia Hayes, chief consultant for VA"s veterans strategic health care group, said that the agency recognizes issues and is making changes to address disparities in care. She noted that VA is creating a long-term plan for construction improvements to address space and building layout challenges (AP/Boston Globe, 7/15).
The U.S. Food and Drug Administration approved Onsolis, medication intended for certain patients with cancer to help manage breakthrough pain - severe flares of pain that break through regular pain medication.
The American Nurses Association (ANA), which represents the interests of the nation"s 2.9 million registered nurses, is joining forces with the Texas Nurses Association (TNA) to strongly criticize the recent indictment and prosecution of two registered nurses in Winkler County, Texas, for reporting to the Texas Medical Board their concerns about a physician"s standard of practice at the Winkler County Memorial Hospital in Kermit, Texas. ANA and TNA are gravely concerned about the chilling effect the county"s actions could have on future nurse "whistle blowers" who advocate for their patients in the nation"s hospitals. An initial hearing on the nurses" motions to dismiss the case was held July 15 in the Winkler County Courthouse but no rulings were made on any of the motions.
When hospitalists use discharge communication software, patients and the outpatient doctors who carry out the care have better perceptions of the quality of the discharge process, according to new research published in the August issue of the Journal of Hospital Medicine.
A person who has exercised regularly prior to the onset of a stroke appears to recover more quickly, say researchers from Mayo Clinic in Florida, who led a national study.
This statement updates Members on the Influenza A (H1N1v) swine flu outbreak and the latest developments in Wales and across the UK.
Following Gordon Brown"s meeting at Downing Street with Britain"s top drinks industry executives he called for them to harness their considerable marketing powers to drive for change in social norm and cultural attitudes towards alcohol in the UK. This has resulted in Project "N" - a collaboration of the not inconsiderable res of top companies throughout the UK.
Gliomas are among the most common and most malignant brain tumors. These tumors infiltrate normal brain tissue and grow very rapidly. As a result, surgery can never completely remove the tumor. Now, the neurosurgeons Dr. Darko S. Markovic (Helios Klinikum Berlin-Buch) and Dr. Michael Synowitz (Charit̩) as well as Dr. Rainer Glass and Professor Helmut Kettenmann (both Max Delbr̿ck Center for Molecular Medicine, MDC, Berlin-Buch), have been able to show that glioma cells exploit microglia, the immune cells of the brain, for their expansion (PNAS Early Edition)*.
Researchers at Georgia State University have found that diets high in fructose - a type of sugar found in most processed foods and beverages - impaired the spatial memory of adult rats.
Those travelling abroad should take seriously advice to pack their condoms and keep their needles to themselves: research published today in the open access journal Retrovirology shows that tourists, travellers and migrants from Greece, Portugal, Serbia and Spain actively export HIV-1 subtype B to other European nations.
Based on serum bank material, BA profiling was applied in IBD patients and healthy controls which showed that most but not all BA species were decreased to a different extent in CD and UC. BA decreases were highly pronounced in CD patients with surgical interventions in the gut. On the other hand, UC patients with additional liver and gallbladder diseases showed clearly increased levels of those BAs that are synthesized directly in the liver (primary BAs), or subsequently modified by intestinal bacteria (secondary BAs). Furthermore, a marked decrease in the toxic BA lithocholic acid (LCA) was found together with a marked increase in its physiological detoxification product, hyodeoxycholic acid (HDCA), irrespective of the IBD phenotype or clinical manifestation, which showed accelerated detoxification activity in IBD patients. Thus, serum BA profiling might serve as an additional diagnostic tool for IBD characterization and differentiation. In combination with expression profiles of nuclear pregnane X receptor (PXR)-regulated genes, it might allow us to estimate the BA detoxification potential of IBD patients.
Early results of a trial in Uganda showed that circumcising men with HIV did not protect their female partners, and as circumcision does not
WHO publishes its first guidelines on indoor air quality, addressing dampness and mould (WHO guidelines on indoor air quality: dampness and mould. Copenhagen, WHO Regional Office for Europe, 2009 (See Here).
A team led by researchers from the National Institutes of Health reports
Correspondence and a linked Editorial in this week"s Lancet criticise the election tactics employed by the British National Party (BNP) prior to the recent European Elections.
THIS month, Cancer Research UK is set to unveil a brand new national television ad campaign to raise awareness and increase donations for vital research into cancer.
Bionovo, Inc. (Nasdaq: BNVI) announced that a study of the gene regulation in multiple cell lines by several of their estrogen receptor beta (ERb) candidates will be published in Public Library of Science One.
A protein in influenza virus that helps it multiply also damages lung epithelial cells, causing fluid buildup in the lungs, according to new research from the University of Alabama at Birmingham (UAB) and Southern Research Institute . Publishing online this week in the journal of the Federation of American Societies for Experimental Biology, the researchers say the findings give new insight into how flu attacks the lungs and provides targets for new treatments.
Highly intelligent adults with Asperger Syndrome still have difficulties in day-to-day social interaction. These difficulties may be explained by "mindblindness", the idea that they are unable to predict what other people will do by thinking about their mental states, that is, their knowledge and beliefs. If this is true then why do people with Asperger syndrome pass all the standard tests of mental state attribution? Is the theory wrong or are the tests insensitive? This study reports evidence from eye movements, that adults with Asperger Syndrome do not spontaneously anticipate another person"s behaviour on the basis of that person"s mental state. This is in stark contrast with typical adults, and even young toddlers.
At a technical breakfast, Romain Quidant presented his research into the detection and treatment of cancer using gold nanoparticles illuminated with laser light. Quidant, who was recently awarded the Fresnel Prize 2009 that recognizes the highest level of excellence amongst emerging researchers in the field of photonics, is an ICREA researcher at the UPC"s Institute of Photonic Sciences (ICFO) and a fellow of the Cellex Foundation Barcelona.
Pain symptoms that cannot be attributed, or at least not fully attributed, to an organic origin are more frequently and more severely experienced by patients with depression than by those without. "It is the case that women are much more frequently affected by depression and also by so-called somatoform pain disorder than men," explains Dirk Frieser, psychologist at the Institute of Psychology at Johannes Gutenberg University Mainz. For the purposes of his doctoral dissertation, Frieser and fellow psychologist Stephanie Kç¶rber questioned 308 patients attending two practices of general practitioners in Mainz. Patients were asked about their state of health and their pain symptoms, but also about their anxieties with regard to illness, how they react when ill, what social support they receive, and what psychological stress they experience, together with many other aspects. Subsequently, the pain symptoms reported by the patients were evaluated by their doctors.
Senate Republicans on Thursday said that they do not plan to block a vote on Supreme Court nominee Sonia Sotomayor, the Washington Post reports. Senate Judiciary Committee ranking member Jeff Sessions (R-Ala.) told Sotomayor that he would not support any effort to filibuster her nomination, meaning that she would need a simple majority of 50 votes to be confirmed. Because Democrats hold 60 votes in the Senate, Sessions" comments effectively end "any possible suspense over her fate," according to the Post (Kane et al., Washington Post, 7/17). Sessions said, "I will not support and I don"t think any member of this side will support a filibuster or any attempt to block a vote on your nomination," adding, "I look forward to you getting that vote before we recess in August." According to CQ Politics, Sessions" statement that Republicans will not filibuster "is bound to rile conservative activists," who have urged GOP senators to delay the vote to allow more time to build opposition.Sen. Lindsey Graham (R-S.C.) also signaled that he would vote for Sotomayor"s confirmation (Perine, CQ Politics, 7/16). He said, "We"ll see what your future holds, but I think it"s going to be pretty bright" (Bendavid, "Washington Wire," Wall Street Journal, 7/16). Sen. James Inhofe (R-Okla.) said that although he will not support Sotomayor"s confirmation, he will not filibuster the vote (Rushing, The Hill, 7/16). Sen. Tom Coburn (R-Okla.) told Sotomayor, "Thank you for giving us such a cordial response, and I am mightily impressed" (Washington Post, 7/17).Voting Timeline UnclearSenate Judiciary Committee Chair Patrick Leahy (D-Vt.) said he would schedule a committee vote on the nomination for July 21. It remains unclear whether committee Republicans will delay the vote until July 28, as they are permitted to do under committee rules. Sessions called the July 21 vote "unrealistic," adding that there "will be a number of questions submitted to the nominee that take some time" (CQ Politics, 7/16). A party-line vote on the nomination does not seem likely, as a number of committee Republicans have praised Sotomayor and signaled that they will vote to confirm her, the AP/Boston Globe reports (Holland, AP/Boston Globe, 7/17). The committee"s vote serves as a recommendation to the full Senate, which likely will hold its final roll-call vote on the nomination by Aug. 7 (Washington Post, 7/17). Senate Majority Leader Harry Reid (D-Nev.) on Thursday said he wants a floor vote on Sotomayor "as quickly as possible" (Brady, Roll Call, 7/16).During the hearing on Thursday, Sotomayor reiterated that she would consider each case individually and declined to state her specific views on abortion rights. In response to Coburn, she said, "Would you want a ... nominee who came in here and said, "I agree with you. This is unconstitutional," before I had a case before me?" She added, "I don"t know that that"s a justice that I can be" (Kiely/Biskupic, USA Today, 7/17). According to the New York Times, "Some observers thought they detected her tipping her hand on abortion rights when she said Supreme Court precedents required abortion restrictions to make exceptions for a woman"s health" (Savage, New York Times, 7/17).
A new study finds more veterans being diagnosed with mental health issues. The study was posted Thursday on the web site of The American Journal of Public Health.
The U.N. Office for the Coordination of Humanitarian Affairs (OCHA) issued an alert on Thursday "seeking donor help" to address the health situation in southern and central Somalia, "which has continued to deteriorate due to latest fighting in [the capital of] Mogadishu," Xinhua reports. In the alert, OCHA said civil strife has had a "debilitating effect" on the social services infrastructure - particularly health services - in the country, Xinhua writes. "With the country already facing one of the highest infant and maternal mortality rates in the world, the humanitarian health community is finding itself constrained by the health funding deficit, leaving a number of critical life-saving health projects uninitiated and ongoing ones under threat of cessation," OCHA said.
The Department of Justice on Thursday said that it is a violation of the Americans with Disabilities Act to bar people -- such as barbers, masseuses, and home health care aides -- from receiving professional licenses or training at occupational schools because they have HIV or AIDS, the AP/Los Angeles Times reports. Some states, for example, require that cosmetologists be free of communicable diseases. "The government says that type of regulation is outdated and was not intended to bar people with HIV. The original goal of such a rule was to prevent the spread of tuberculosis and other diseases, not prevent people with [HIV] from working in certain fields," according to the AP/Times. Furthermore, "The Supreme Court has found people with AIDS or HIV are covered under the law barring discrimination against people with disabilities," the article states (7/16).
Hebrew SeniorLife has received a $105,000 grant from the Tufts Health Plan Foundation for the expansion and implementation of three evidence-based healthy aging programs designed to disseminate preventive health-related information to seniors in the community.
The aloe vera plant has a long history of healing power. Its ability to heal burns and cuts and soothe pain has been documented as far back as the 10th century. Legend has it that Cleopatra used aloe vera to keep her skin soft. The modern use of aloe vera was first recognized the 1930s to heal radiation burns. Since then, it has been a common ingredient in ointments that heal sunburn, minor cuts, skin irritation, and many other ailments. Recently, aloe vera has gained some popularity as an active ingredient in tooth gel. Similar to its use on skin, the aloe vera in tooth gels is used to cleanse and soothe teeth and gums, and is as effective as toothpaste to fight cavities, according to the May/June 2009 issue of General Dentistry, the Academy of General Dentistry"s (AGD) clinical, peer-reviewed journal.
The June cover of the Journal of Virology features a photograph of the unusual effects on a cell infected by a virus. Montana State University researchers were the first to view the virus, which they collected from a boiling, acidic spring in Yellowstone.
TECNALIA CorporaciÃön TecnolÃögica and the Valencia Institute for Biomechanics (IBV) have designed made-to-measure solutions to improve adaptation to replacements for amputated legs - the prime objective of the new health biomaterials project, FABIO, financed by the Ministry of Industry, Trade and Tourism.
A study which found up to one third of GPs are planning to retire early highlights the need for governments to boost support for general practice, AMA Federal President, Dr Andrew Pesce, said today.
Pablo A. Celnik, M.D., an assistant professor of physical medicine and rehabilitation and neurology at the Johns Hopkins University School of Medicine, and Thao (Vicky) Nguyen, 32, assistant professor of mechanical engineering in the Whiting School of Engineering at The Johns Hopkins University, are among the 100 winners of this year"s Presidential Early Career Award for Scientists and Engineers (PECASE).
A major research grant will help scientists study the links between memory and oral health in a bid to establish control over Alzheimer"s disease.
King Saud University professor, Dr. Adel Almogren, along with a diverse team of academic researchers from the United States, Canada, and Taiwan, has discovered a new process that could lead to a vaccine to block cancer cell adhesion and growth.
Human Genome Sciences, Inc. (Nasdaq: HGSI) and GlaxoSmithKline PLC (GSK) announced that BENLYSTA(TM) (belimumab, formerly LymphoStat-B(R)) met the primary endpoint in BLISS-52, the first of two pivotal Phase 3 trials in patients with serologically active systemic lupus erythematosus (SLE). In the placebo-controlled BLISS-52 study, the results showed that belimumab plus standard of care achieved a clinically and statistically significant improvement in patient response rate at Week 52, compared with standard of care alone. Study results also showed that belimumab was generally well tolerated, with adverse event rates comparable between belimumab and placebo treatment groups.
Scientists have worked for 20 years to perfect gene therapy for the treatment of cystic fibrosis, which causes the body to produce dehydrated, thicker-than-normal mucus that clogs the lungs and leads to life threatening infections.
In a proof-of-concept study, Mayo Clinic investigators have demonstrated that induced pluripotent stem (iPS) cells can be used to treat heart disease. iPS cells are stem cells converted from adult cells. In this study, the researchers reprogrammed ordinary fibroblasts, cells that contribute to scars such as those resulting from a heart attack, converting them into stem cells that fix heart damage caused by infarction. The findings appear in the current online issue of the journal Circulation.
Congratulations to the winners of the 2009 Avant/AMSA Student Research Fellowship:
Latest research on proton therapy highlights medical physics meeting next week in Anaheim
The Washington Post reports that Regina Benjamin -- President Obama"s nominee for U.S. surgeon general -- shares Obama"s position on reproductive health issues, a position that could put her "at odds" with the Catholic Church"s positions on reproductive rights, according to s familiar with her selection. White House spokesperson Reid Cherlin said, "Like [Obama], she believes that this is an issue where it is important to try and seek common ground and come together to try and reduce the number of unintended pregnancies." Cherlin added, "As a physician, she is deeply committed to the philosophy of putting her patients" needs first when it comes to providing care." The White House would not specifically comment on her views on abortion rights, and an HHS spokesperson says Benjamin is not permitted to speak publicly until she is confirmed. s close to Benjamin, who is Catholic, say that she does support abortion rights, the Post reports. However, several individuals who know Benjamin said her views would not affect her role as surgeon general. David Satcher -- a surgeon general in the Clinton administration who taught community health to Benjamin at the Morehouse School of Medicine -- said, "We all have our religions, but when you speak as the surgeon general to the American people, it"s not about your religion." He added, "I don"t see why the surgeon general has to get involved in a discussion about abortion." Jorge Alsip -- president of the Medical Association of the State of Alabama -- said abortion-related issues occasionally arose when he and Benjamin served on the Alabama State Committee on Public Health. Alsip, who is Catholic, said he does not know her position on the issue, adding, "You kind of have to park your personal beliefs at the door when they conflict with what your role is."Sister Carol Keehan, president and CEO of the Catholic Health Association, said, "This is not pivotal to the surgeon general"s job." She added, "From the perspective of being a practicing Catholic, you can certainly say that it matters. I think being willing to work to reduce (abortion) is a good thing."Robert Lawrence, a director at Johns Hopkins University"s Bloomberg School of Public Health and chair of the board of Physicians for Human Rights, served with Benjamin on the group"s board from 1996 until 2002. He said, "I would think that as surgeon general she would uphold the law of the land, and the law of the land guarantees women a choice for reproductive health." He added, "The charge of the surgeon general is to be the people"s doctor and ensure that all those health services guaranteed under federal law are available to the people" (Thompson, Washington Post, 7/19).
Routine screenings for cancers -- including breast cancer in younger women -- have not proven to reduce the chance of death for people without specific symptoms or risk factors, and experts suggest that some tests could lead to harm, the New York Times reports.According to Ned Calonge, chair of the United States Preventive Services Task Force, screening is only useful if it prevents enough deaths to outweigh harm from treatments that are not medically necessary. He said that although screening in some cases will detect life-threatening cancers that respond to intervention, it also can result in false positives that cause needless worry and unnecessary procedures. Screening also might fail to diagnose an existing cancer, causing patients to ignore symptoms; find slow-growing or stable cancers that are not life-threatening and normally do not need treatment; or find aggressive, life-threatening cancers that do not respond to treatment, Calonge said. Only a handful of screening tests have been proven to significantly reduce death among certain age groups: pap tests to screen for cervical cancer beginning no later than age 21; mammograms to screen for breast cancer starting at age 40; and colon cancer screening beginning at age 50. According to the Centers for Disease Control and Prevention, there is no medical proof that routine screening for many other cancers -- including ovarian cancer -- reduces deaths.The Times reports that the Breast Cancer Education and Awareness Requires Learning Young Act of 2009 (HR 1740) -- also known as the Early Act -- has become a central issue in the debate because it would create a breast cancer detection campaign for women younger than age 45. Rep. Debbie Wasserman-Schultz (D-Fla.) introduced the bill in March, and it now has more than 350 co-sponsors. The bill would provide $45 million over five years for teaching young women and their physicians to check for abnormalities; promote healthy lifestyle choices; and provide grants to groups supporting women with breast cancer. The bill focuses on certain ethnic or racial groups at higher risk of developing aggressive tumors. CDC would oversee an expert panel to create the campaign based on the latest medical research, Wasserman-Schultz said.Critics of the bill say that the legislation promotes techniques, such as self-exams, that have not proven to detect cancer at earlier stages or reduce deaths. They also argue that self-exams could lead to many insignificant nodules being biopsied, which can cause scarring and make it harder to detect breast cancer when women are older. According to Susan Love -- a breast cancer surgeon who has encouraged Wasserman-Schultz to abandon the bill -- the public health campaign could cause younger women to overestimate their chances of dying of breast cancer (Singer, New York Times, 7/17).